Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 87-48-9, name is 5-Bromoindoline-2,3-dione, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 87-48-9
General procedure: Isatin or 5-substituted isatin (7 mmol) and K2CO3 (10 mmol) were added to a dry CH3CN solution (25 mL) and stirred for 30 min at RT. Methyl iodide or benzyl chloride (7.5 mmol) was added to the solution and then refluxed at 80C for 3 hour. The mixture was cooled to RT and the solvent was removed. The residue was dissolved in CH2Cl2(30 mL) and then washed with H2O (3×30 mL). The organic extracts were dried over anh Na2SO4 and concentrated to give the crude brown solid. The purification of the crude solid using flash-column chromatography (silica gel, hexane/EtOAc (2:1) gave the pure compounds 3a-g.
According to the analysis of related databases, 87-48-9, the application of this compound in the production field has become more and more popular.
Reference:
Article; Phutdhawong, Weerachai; Rattanopas, Sopita; Sirirak, Jitnapa; Taechowisan, Thongchai; Phutdhawong, Waya S.; Oriental Journal of Chemistry; vol. 35; 2; (2019); p. 723 – 731;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem