Application of 41663-84-7, A common heterocyclic compound, 41663-84-7, name is 2-Methyl-5-nitroisoindoline-1,3-dione, molecular formula is C9H6N2O4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 4 To a reaction vessel containing dimethylacetamide (25 ml) were added 4-nitro-N-methylphthalimide (0.50 g, 0.00243 mol), biphenyl (0.204 g, 0.00132 mol) and sodium hydrogen sulfide (0.14 g, 0.0025 mol). The reaction was allowed to proceed at 70 C. for 24 hours. Samples of the reaction mixture were taken and examined by HPLC methods. A yield of 16.3% 4,4’bis(N-methylphthalimide)sulfide was indicated. The isolated yield was 15% (0.035 g).
The synthetic route of 41663-84-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; General Electric Company; US4625037; (1986); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem