September 22, 2021 News Extracurricular laboratory: Synthetic route of 2058-72-2

Quality Control of 5-Bromo-1-methylindoline-2,3-dione,When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process.

Quality Control of 5-Bromo-1-methylindoline-2,3-dione,When developing chemical systems it’s of course important to gain a deep understanding of the chemical reaction process.

General procedure: 11H-indeno[1,2-b]quinoxalin-11-one 2a (0.23?g, 1.00?mmol) and TosMIC (0.20?g, 1.10?mmol) was poured into the mixture of ethanol (1.00?mL) and K2CO3 (0.14?g, 1.00?mmol), and stirred for 10?min?at ambient temperature. After that, the reaction mixture was diluted with water (3.00?mL), the resulting precipitate was filtered, and washed with water.

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Reference:
Article; Shaabani, Ahmad; Sepahvand, Heshmatollah; Bazgir, Ayoob; Khavasi, Hamid Reza; Tetrahedron; vol. 74; 49; (2018); p. 7058 – 7067;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem