Adding a certain compound to certain chemical reactions, such as: 64483-69-8, name is 5-Acetylindolin-2-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 64483-69-8, Recommanded Product: 64483-69-8
The 5-acetyloxindole (54 g, 308 mmol), acetic acid (400 ml) and palladium on carbon (10%, 5 g) are combined and treated with hydrogen for 14 hours at 55 psi. The catalyst is removed by filtering through a bed of Celite, the filtrate is concentrated under reduced pressure and the residue is treated with ether to give 5-ethyloxindole
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 5-Acetylindolin-2-one, and friends who are interested can also refer to it.
Reference:
Patent; Novartis AG; US6291523; (2001); B1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem