Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 675109-45-2, name is 6-Amino-2,3-dihydro-1H-isoindol-1-one, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 675109-45-2
To a solution of 6-amino-2,3-dihydroisoindol-1-one (1.78 g, 12 mmol) in DMF/H2O (2:1, 75 ml) was added K2CO3 (3.32 g, 24 mmol, 2 eq.) and di-tert-butyl dicarbonate (5.67 g, 26 mmol, 2.2 eq.). The reaction was stirred at room temperature overnight. The reaction was partitioned between ethyl acetate and water, and the organic layer was washed with saturated NaCl (aq), dried (MgSO4), filtered and concentrated in vacuo. The residue was triturated with ethyl acetate and the resulting solid was filtered off to afford title compound (2.04 g, 68%). 1H NMR (360 MHz, d6 DMSO) ? 8.48 (1H, s), 7.83 (1H, d, J=1.2 Hz), 7.6 (1H, dd, J=8.2, 1.9 Hz), 7.43 (1H, d, J=8.2 Hz), 4.28 (2H, s), 1.49 (9H, s).
According to the analysis of related databases, 675109-45-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Boase, Amanda Louise; Ladduwahetty, Tamara; MacLeod, Angus Murray; Merchant, Kevin John; US2004/58970; (2004); A1;,
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