Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 14192-26-8, name is Methyl 2-oxoindoline-6-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of Methyl 2-oxoindoline-6-carboxylate
At room temperature, the 6 – methoxy carbonyl -2 – oxo indoline (50g, 0.26 muM) adding toluene (150 ml) in, slowly adding chloroethyl anhydride (67.5g, 0 . 39 muM). The mixture is heated to reflux, and the stirring reaction 2.5h, then cooling to 80 C, and in the system by adding cyclohexane (100 ml), the resulting solution is cooled to room temperature. Filtering, using toluene and washing the solid, and dried, to obtain white solid 65.8g, yield is 94.2%.
According to the analysis of related databases, 14192-26-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shenyang Pharmaceutical University; Qin Mingze; Gong Ping; Zhang Haotian; Zhao Yanfang; (39 pag.)CN106565682; (2017); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem