Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 16800-68-3, name is 1-Acetylindolin-3-one, A new synthetic method of this compound is introduced below., SDS of cas: 16800-68-3
The N- acetyl-3-indolyl-one 1.75g (10mmol), 1,2- dimethyl-indole 1.35g (10mmol) and cuprous iodide 0.19g (1.0mmol) was dissolved in ethanol, was heated to 60 C after 12 hours the reaction, extracted with dichloromethane, the organic layers combined, dried over anhydrous sodium sulfate, dichloromethane / methanol to give a white solid product was recrystallized from N- acetyl -3- (indol-3-methyl-N- ) – indole (2.8g, yield 92%),
The synthetic route of 16800-68-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Sun Yat-sen University; Weng, Jiang; Lu, Gui; Guo, Jing; (7 pag.)CN105669516; (2016); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem