Adding a certain compound to certain chemical reactions, such as: 611-09-6, name is 5-Nitroindoline-2,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 611-09-6, Application In Synthesis of 5-Nitroindoline-2,3-dione
General procedure: Dimedone (0.280 g, 2 mmol) and isatin (0.147 g, 1 mmol) weremixed in oxalic acid: proline LTTM (5 mL) as solvent and the resultantmixture was heated at 90 C for appropriate time. After the completionof the reaction indicated by TLC, mixture was stirred at room temperatureand 5 mL distilled water was added. The insoluble crude productwas filtered, washed with distilled water and recrystallized from ethanolto obtain pure product.
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Reference:
Article; Chandam; Patravale; Jadhav; Deshmukh; Journal of Molecular Liquids; vol. 240; (2017); p. 98 – 105;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem