Extended knowledge of 181140-34-1

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 181140-34-1, name is (R)-(-)-N-(2,3-Epoxypropyl)phthalimide, A new synthetic method of this compound is introduced below., COA of Formula: C11H9NO3

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 181140-34-1, name is (R)-(-)-N-(2,3-Epoxypropyl)phthalimide, A new synthetic method of this compound is introduced below., COA of Formula: C11H9NO3

General procedure: Suspension of starting compound (2a-e) and (S)-N-(2,3-epoxypropyl)phthalimide or (R)-N-(2,3-epoxypropyl)phthalimide (1 eq.) in absolute ethanol (0.2 M) was refluxed for 15 h. The crude product precipitated from clear solution at 0 C. Compounds 3a-f were purified either by flash column chromatography using EtOAc/hexane as eluant or by recrystallization from absolute ethanol.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Trstenjak, Uro?; Ila?, Janez; Kikelj, Danijel; European Journal of Medicinal Chemistry; vol. 64; (2013); p. 302 – 313;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem