Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2058-72-2, name is 5-Bromo-1-methylindoline-2,3-dione, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 5-Bromo-1-methylindoline-2,3-dione
In a 50 mL reaction flask,Triethylamine (40 mg, 0.4 mmol)Was added to a solution of 1-methyl-5-bromoisatin (240 mg, 1.0 mmol)1-cyanoacetylguardane azulene (344 mg, 1.3 mmol)And malononitrile (86 mg, 1.3 mmol)In acetonitrile (30 mL)Heated to reflux for 7 hours (monitored by silica gel chromatography (TLC)). After completion of the reaction,The reaction mixture was concentrated under reduced pressure and recrystallized from acetic acid to give a blue solid in 80% yield.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2058-72-2.
Reference:
Patent; Bohai University; Wang Daolin; Zhang Weinan; Xing Jinjuan; (14 pag.)CN106220641; (2016); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem