Adding a certain compound to certain chemical reactions, such as: 5332-26-3, name is 2-(Bromomethyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5332-26-3, Recommanded Product: 5332-26-3
Salt (n-Bu4N)2[2-B10H9SH] (0.50g, 0.79mmol), N-(bromomethyl)phthalimide (0.19g, 0.84mmol), and cesium carbonate (0.26g, 0.39mmol) were placed in a 25-ml round-bottom flask and dissolved in 4ml DMF. The solution was heated to 40C in an argon atmosphere for 2h. After cooling to room temperature, a precipitate was removed by filtration and the solvent was distilled off on a rotary evaporator, and the dry residue was resuspended in 15ml of distilled water and allowed to stand in an ultrasonic bath to form a flocculated suspension. The precipitate was filtered off and washed with distilled water (2×10ml) and ethyl acetate (3×5 ml). Yield: 94%. Anal. calc. for C41H87B10N3O2S (%): C, 61.99; H, 11.04; N, 5.29; S, 4.04. Found (%): C, 61.72; H, 11.12; N, 5.15; S, 3.90. (0013) 1H NMR (CD3CN, delta, ppm): 7.74 (m, 4H, Ph), 4.24 (s, 2H, SCH2), 3.11 (m, 8H, n-Bu4N+), 1.61 (m, 8H, n-Bu4N+), 1.35 (m, 8H, n-Bu4N+), 0.96 (t, 12H, n-Bu4N+), 0.60-2.10 (m, 9H, B10H9). (0014) 13C NMR (CD3CN, delta, ppm): 168.3 (CO), 134.8, 133.4, 123.6 (Ph), 59.3 (n-Bu4N+), 41.5 (SCH2), 24.4 (n-Bu4N+), 20.3 (n-Bu4N +), 13.8 (n-Bu4N +). (0015) 11B-{1H} NMR (CD3CN, delta, ppm): -0.1 (d, 1B), -2.6 (d, 1B), -16.6 (s, 1B), -24.9 (d, 4B), -27.6 (d, 2B), -28.8 (d, 1B). (0016) IR (CCl4): 3467, 3087, 3070, 3042, 3030, 2978, 2950, 2875, 2500, 2477, 1773, 1702, 1614, 1455, 1439, 1401, 1372, 1318, 1190, 1158, 1107, 1083, 1010, 987, 941, 875,790, 711, 644, 605, 520cm-1.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(Bromomethyl)isoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Kubasov; Turishev; Golubev; Bykov, A.Yu.; Zhizhin, K.Yu.; Kuznetsov; Inorganica Chimica Acta; vol. 507; (2020);,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem