Related Products of 7147-90-2, These common heterocyclic compound, 7147-90-2, name is 5-Chloroisoindoline-1,3-dione, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Example 7 4-Chloro-N-amino phthalimide STR34 To a cooled mixture of 1.81 g (10 mmol) 4-chloro phthalimide in 20 mL ethanol (96%) was added 0.5 mL (10 mmol) hydrazine monohydrate. The reaction mixture was stirred for 2 min. at room temperature and 2 min. at reflux. By adding 50 mL cold water pale yellow crystals formed alter 1 h. Resulting crystals was filtered and recrystallized from ethanol to give 0.4 g (20%) 4-chloro-N-amino-phthalimide:
The synthetic route of 7147-90-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hay; Allan S.; Ghassemi; Hossein; US5359092; (1994); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem