Adding a certain compound to certain chemical reactions, such as: 89-40-7, name is 5-Nitroisoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 89-40-7, Recommanded Product: 5-Nitroisoindoline-1,3-dione
5: A mixture of 4-nitro-phthalimide 4 (8.02 g, 0.042 mol) and hydrochloric acid (26 %, 290 mL) was heated at 50 C for 2 h. Then the resulted yellow solution was cooled to room temperature. The precipitate was collected by filtration and recrystallized from ethanol dried in vacuum affording a light yellow solid 5 (7.44 g, 89% yield). 1H NMR (DMSO-d6): delta (ppm) 10.77 (s, 1H, CONHCO), 7.45 (d, J1 = 8.0, 1H, Ar-H), 6.92 (d, J2 = 2.0 Hz, 1H, Ar-H), 6.86 (dd, J1= 8.0, J2 = 2.0 Hz, 1H, Ar-H). 5.06 (s, 2H, NH2). 13CNMR (DMSO-d6): delta (ppm) 169.44, 169.26, 150.64, 135.22, 124.73, 121.51, 120.11, 109.64.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Nitroisoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Song, Xiaoyu; Zhao, Jing; Zhang, Wandong; Chen, Long; Chinese Chemical Letters; (2018); p. 331 – 335;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem