Adding some certain compound to certain chemical reactions, such as: 14192-26-8, name is Methyl 2-oxoindoline-6-carboxylate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 14192-26-8. 14192-26-8
A mixture of methyl oxindole-6-carboxylate (11.47 g) and acetanhydride (32 ml) was stirredat the bath temperature of 138C; a clear red solution was produced within 10 mm. Thereaction mixture was stirred at 138C for 6 h, then left to stand at 20C for 4 h and the crystallization of the product was completed in 2 h at 10C. The product was filtered off, washed with petroleum ether and finally with glacial methanol. The yield was 12.15 g (87%) of reddish crystals
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of Methyl 2-oxoindoline-6-carboxylate.
Reference:
Patent; ZENTIVA, K.S.; MECA, Ludek; (16 pag.)WO2017/16530; (2017); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem