In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 3676-85-5 as follows. HPLC of Formula: C8H6N2O2
15 g of 5-aminophthalimide was added to 105 g of water and to this mixture, 39 g of a 35% aqueous hydrochloric acid was added dropwise. The reaction was kept at temperatures no higher than 5C and 48.7 g of a 16% aqueous sodium nitrite was added dropwise. Thereafter, the reaction was kept at temperatures from -2 to 2C for 120 minutes with stirring and the insoluble matter was removed by suction filtration to give an aqueous 5-diazophthalimide chloride.
According to the analysis of related databases, 3676-85-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo; EP1650267; (2006); A1;,
Indoline – Wikipedia,
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