Adding a certain compound to certain chemical reactions, such as: 954-81-4, name is N-(5-Bromopentyl)phthalimide, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 954-81-4, Application In Synthesis of N-(5-Bromopentyl)phthalimide
General procedure: To a suspension of compound 9-12 and potassium carbonate in ACN, was added dropwise N-methylbenzylamine or piperidine under stirring and the reaction mixture was refluxed for 24 h. The reaction mixture was cooled and filtered. After evaporation of the filtrate, purification by column chromatography on silica gel (cyclohexane/EtOAc/TEA) yielded compounds 16 and 17.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, N-(5-Bromopentyl)phthalimide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Ghedira, Donia; Voissiere, Aurelien; Peyrode, Caroline; Kraiem, Jamil; Gerard, Yvain; Maubert, Elise; Vivier, Magali; Miot-Noirault, Elisabeth; Chezal, Jean-Michel; Farhat, Farhat; Weber, Valerie; European Journal of Medicinal Chemistry; vol. 158; (2018); p. 51 – 67;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem