Continuously updated synthesis method about 56341-37-8

Adding a certain compound to certain chemical reactions, such as: 56341-37-8, name is 6-Chlorooxindole, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 56341-37-8, Recommanded Product: 6-Chlorooxindole

Adding a certain compound to certain chemical reactions, such as: 56341-37-8, name is 6-Chlorooxindole, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 56341-37-8, Recommanded Product: 6-Chlorooxindole

General procedure: To a solution of s7 (398 mg, 1.18 mmol) in EtOH (2.30 mL) were successively added addedoxindole (105 mg, 1.13 mmol) and piperidine (12 muL, 0.12 mmol) at room temperature. After 20 h,the reaction mixture was concentrated in vacuo. The residue was purified by columnchromatography (silica gel, hexane/EtOAc = 4/1) to afford aldehyde 1a (422 mg, 84%) as yellowsolid, whose geometry was determined by X-ray crystal analysis.

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Reference:
Article; Machida, Mizuki; Mori, Keiji; Chemistry Letters; vol. 47; 7; (2018); p. 868 – 871;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem