Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3783-77-5, name is 2-(3-Oxobutyl)isoindoline-1,3-dione, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C12H11NO3
Synthesis of 2-(4-bromo-3-oxo-butyl)-isoindole-1 ,3-dione (C12H10NO3Br, MW = 294.98) To an ice-cooled and well-stirred suspension of 2-(3-oxo-butyl)-isoindole-1 ,3-dione (30.0 g, 138 mmol, 1 eq.) in MeOH (180 mL), bromine (14.3 mL, 276 mmol, 2 eq.) was added in one portion. The resulting red heterogeneous mixture was stirred at 0 C for 5 min., and further at r.t. for 3.5 hours. The orange homogeneous reaction mixture was then treated with 10M aq. H2SO4 soln. (26.2 mL). The resulting heterogeneous mixture was further stirred at r.t. for 2 hours. The resulting heterogeneous reaction mixture was filtered in order to isolate the target product as a white-off solid which was further dried under high vacuum. The product was used without further purification. LC-MS 3: tR = 0.76 min; [M+Hf = 296.1
According to the analysis of related databases, 3783-77-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ACTELION PHARMACEUTICALS LTD; AISSAOUI, Hamed; BOSS, Christoph; RICHARD-BILDSTEIN, Sylvia; SIEGRIST, Romain; WO2014/6585; (2014); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem