Related Products of 39603-24-2, A common heterocyclic compound, 39603-24-2, name is 5,7-Dimethylindoline-2,3-dione, molecular formula is C10H9NO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of isatin derivatives or acenaphthenquinone(1 mmol), barbituric acid (1 mmol), 1, 3-dicarbonyl compounds(1 mmol), SBDBSAC (0.02 g) and H2O (5 mL) was added to a in a25 mL round-bottomed flask connected to a reflux condenser, andstirred under reflux conditions. After completion of the reaction, asmonitored by TLC, the reaction mixture was cooled to room temper-ature. Methanol (20 mL) was added, stirred and refluxed for 3 min.Then, the resulting mixture was centrifuged for the separation of the catalyst from the product and remaining starting materials.After the separation of catalyst from the reaction mixture, methanolwas removed and the solid residue (crude product) was trituratedby a mixture of ethanol and water (9/1) to give the pure product.
The synthetic route of 39603-24-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Moosavi-Zare, Ahmad Reza; Zolfigol, Mohammad Ali; Noroozizadeh, Ehsan; Moratab, Rasoul Salehi; Zarei, Mahmoud; Journal of Molecular Catalysis A: Chemical; vol. 420; (2016); p. 246 – 253;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem