2058-72-2, Adding some certain compound to certain chemical reactions, such as: 2058-72-2, name is 5-Bromo-1-methylindoline-2,3-dione, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2058-72-2.
To a stirred mixture of isocyanoacetate 1 (0.12 mmol),2-MeOC6H4CO2H (10 mol%), 4a (10 mol%), and AgPF6 (11 mol%)in THF (0.5 mL) was added isatin 2 (0.1 mmol) and THF (0.5 mL)at 0 C. The reaction was then allowed to proceed at 0 C for 4-6h. Upon completion, the reaction mixture was purified by flashchromatography on silica gel to afford the desired product.Analytical data of some typical compounds:
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2058-72-2.
Reference:
Article; Lu, Yan; Wang, Min; Zhao, Xiaohu; Liu, Xiaohua; Lin, Lili; Feng, Xiaoming; Synlett; vol. 26; 11; (2015); p. 1545 – 1548;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem