Adding a certain compound to certain chemical reactions, such as: 161596-47-0, name is (S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 161596-47-0, Recommanded Product: 161596-47-0
((S)-2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.56g, 22.46mmol, 1.3eq.) and 4-(4-isocyanatophenyl)morpholin-3-one (3.77g, 17.29mmol) were dissolved in isoamyl acetate (70mL) respectively, and heated to 120C. Then magnesium chloride (0.12g, 1.28mmol) was added, the mixture was reacted for 4h, white solid was obtained by filtration (6.97g, yield:95.5%). ESI-MS(m/z): 422(M+H), 444(M+Na); 1HNMR(400MHz, CDCl3) delta: 3.74(m, 2H), 3.94(m, 4H), 4.10(m, 2H), 4.32(s, 2H), 4.98(m, 1H), 7.34(d, 2H), 7.56(d, 2H), 7.75(m, 2H), 7.88(m, 2H); HPLC: 98.82%
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.