In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2058-72-2, name is 5-Bromo-1-methylindoline-2,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below. 2058-72-2
General procedure: Triethanolamine (20 mol %) wasadded to a solution of 1,2-benzoxathiin-4(3H)-one 2,2-dioxide(1) (0.198 g, 0.001 mol), malononitrile (2) (0.066 g,0.001 mol), and appropriate isatin 3a-n (0.001 mol) in EtOH (5-10 ml). The mixture was refluxed for 1 h. The obtained precipitates of compounds 4a-n were filtered off,washed with EtOH, dried in air, and recrystallized from EtOH-DMF, 1:1.
The synthetic route of 2058-72-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Grygoriv, Galina V.; Lega, Dmitry A.; Zaprutko, Lucjusz; Gzella, Andrzej K.; Wieczorek-Dziurla, Ewa; Chernykh, Valentine P.; Shemchuk, Leonid A.; Chemistry of Heterocyclic Compounds; vol. 55; 3; (2019); p. 254 – 260;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem