3891-07-4, name is 2-(2-Hydroxyethyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. name: 2-(2-Hydroxyethyl)isoindoline-1,3-dione
0.50 g of N-(2-hydroxyethyl)phthalimide, 10 mL of thionyl chloride, 2 drops of DMF, reflux for 5.0 h.Reaction is complete, cooling, 10% NaHCO33The solution was neutralized to neutral and extracted with ethyl acetate. The organic layer was dried and desolvated to give a solid. The crude product was recrystallized to give a pale yellow solid (0.46 g), yield 83.9%.
The synthetic route of 3891-07-4 has been constantly updated, and we look forward to future research findings.