Extracurricular laboratory: Synthetic route of 2-(4-Bromobutyl)isoindoline-1,3-dione

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Adding a certain compound to certain chemical reactions, such as: 5394-18-3, name is 2-(4-Bromobutyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5394-18-3, category: indolines-derivatives

To the reaction flask was added 0.1 part of sodium hydride, 0.1 part of imidazole, 20 parts of tetrahydrofuranwere mixed evenly. Then, 0.08 parts of compound 1 was slowly added in dropwise manner, reacted at a temperatureat 50 for 1 h, filtered and air dried to collect compound 2, yield 85.5 %.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.