Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 32372-82-0, name is Isoindoline hydrochloride, A new synthetic method of this compound is introduced below., Recommanded Product: Isoindoline hydrochloride
To concentrated sulphuric acid (3 mL) at -10C was added isoindoline hydrochloride (1.569 g). The mixture was stirred at -10C for 15 min. Fuming nitric acid (3 mL) was added drop-wise. The resulting mixture was stirred for 35 min at room temperature and then heated up and stirred at 50 C for 35 min. After cooling to room temperature, the mixture was diluted with ethyl acetate (5 mL) and poured onto ice-water. The resulting precipitate was collected, washed with small amount of ethyl acetate and dried to afford 5-nitroisoindoline hydrosulfate 1 (1.644 g, 62.7%).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.