1074-82-4, Name is Potassium 1,3-dioxoisoindolin-2-ide, 1074-82-4, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
General procedure: In a round bottomed flask (100mL), it was added potassium phthalimide (1.85g, 0.01mol) and desire 1,n-dibromoalkane (0.02mol) in the presence of a catalytic amount of TBAI (0.1g) in anhydrous DMF (10mL). The reaction was stirred for 24h at r.t. After the completion of the reaction (TLC check), the solvent was evaporated in vacuo and the remaining residue was diluted in CHCl3 (150mL) and washed with H2O (3¡Á150mL). The organic phase was evaporated and the remaining residue was purified by a short column chromatography on silica and n-hexane as an eluent.
Statistics shows that Potassium 1,3-dioxoisoindolin-2-ide is playing an increasingly important role. we look forward to future research findings about 1074-82-4.
Reference:
Article; Rad, Mohammad Navid Soltani; Behrouz, Somayeh; Saremi, Hossein; Mohammadtaghi-Nezhad, Javad; Journal of Molecular Liquids; vol. 299; (2020);,
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