Adding a certain compound to certain chemical reactions, such as: 239463-85-5, name is (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 239463-85-5, Recommanded Product: (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate
3- {5 – [(2R) -2-aminopropyl] -7-cyano-2,3-dihydro -1H- indol-1-yl} propyl benzoate (2R, 3R) – mono tartrate 50g(97.5mmol, 1eq ) was poured into methanol 500ml, potassium hydroxide 12g (214mmol, 2.2eq)was reflux for 2 hours stirring was charged. After completion of the reaction, after cooling to room temperature filtered, the filtrate was concentrated (R)-5-(2-aminopropyl) -1- (3-hydroxypropyl) indoline-7-carbonitrile 25 g (100%) It was obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Kyongbo Pharm Company Limited; Son, Feju; Ban, Sonfun; Kwon, Hyok Bom; Yoon, Ik Hwan; Choi, Min-sik; Yang, Jiwon; (15 pag.)JP2016/23186; (2016); A;,
Indoline – Wikipedia,
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