17564-64-6, name is 2-(Chloromethyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 17564-64-6
2.5 g (38.4 mmol) of sodium azide was added to a solution of a commercially available N-(Chloromethyl)phthalimide (25.6 mmol, 5 g) in 50 mL of DMSO. The resulting suspension was stirred at room temperature for 24 h. After adding ice water, the mixture was extracted several times with diethyl ether. The combined organic phases were dried over MgSO4 and the solvent was removed by evaporation under vacuum. Azide 5 was sufficiently pure to be used thereafter (4.810 g, 93% yield).
The synthetic route of 17564-64-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Ben Nejma, Aymen; Znati, Mansour; Daich, Adam; Othman, Mohamed; Lawson, Ata Martin; Ben Jannet, Hichem; Steroids; vol. 138; (2018); p. 102 – 107;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem