Adding a certain compound to certain chemical reactions, such as: 7699-18-5, name is 5-Methoxyindolin-2-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7699-18-5, SDS of cas: 7699-18-5
General procedure: 4.4.2 (Z)-5-methoxy-3-((2-(4-methoxyphenyl)-1H-benzo[d]imidazol-6-yl)methylene)indolin-2-one (5b) Compound 5b was prepared according to the method described for compound 5a, employing aldehyde 11a (126 mg, 0.5 mmol) and 5-methoxyindolin-2-one (12b, 81 mg, 0.5 mmol) to obtain the pure product 5c as a yellow solid (114 mg, 58%); mp: 177-179 C; IR (KBr): 3422, 3153, 2931, 2352, 1681, 1642, 1576, 1474, 1435, 1254, 1179, 1029, 961, 864 cm-1; 1H NMR (300 MHz, DMSO-d6): delta 10.41 (bs, 1H), 8.25-8.16 (m, 3H), 7.82 (s, 1H), 7.72 (d, J = 8.1 Hz, 1H), 7.58 (d, J = 8.3 Hz, 1H), 7.40 (s, 1H), 7.12 (d, J = 8.6 Hz, 2H), 6.82-6.70 (m, 2H), 3.90 (s, 3H), 3.68 (s, 3H); 13C NMR (75 MHz, DMSO-d6): delta 168.9, 160.6, 154.3, 153.7, 153.1, 137.4, 136.2, 128.0, 127.9, 127.6, 126.1, 124.5, 123.7, 122.0, 121.9, 113.9, 109.9, 108.5, 55.0; MS (ESI): m/z 398 [M + H]+; HRMS (ESI): calcd for C24H20O3N3 m/z 398.14923 [M + H]+; found 398.14992.
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Reference:
Article; Kamal, Ahmed; Nagaseshadri; Nayak, V. Lakshma; Srinivasulu, Vunnam; Sathish, Manda; Kapure, Jeevak Sopanrao; Suresh Reddy; Bioorganic Chemistry; vol. 63; (2015); p. 72 – 84;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem