Reference of 6341-92-0, These common heterocyclic compound, 6341-92-0, name is 6-Chloroisatin, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Indole (0.234 g, 2 mmol) and isatin (0.147 g, 1 mmol) were mixed in oxalic acid: proline (5 ml) as solvent and the resultant mixture was stirred at room temperature for appropriate time. After the completion of the reaction indicated by TLC, 5 ml distilled water was added. The insoluble crude product was filtered, washed with distilled water and recrystallized from ethanol.
The synthetic route of 6341-92-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chandam, Dattatray; Mulik, Abhijeet; Patil, Prasad; Jagdale, Suryabala; Patil, Dayanand; Sankpal, Sandeep; Deshmukh, Madhukar; Journal of Molecular Liquids; vol. 207; (2015); p. 14 – 20;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem