The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 161596-47-0, Name is (S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione, SMILES is O=C1N(C[C@@H]2OC2)C(C3=C1C=CC=C3)=O, in an article , author is Lei, Jie, once mentioned of 161596-47-0, HPLC of Formula: C11H9NO3.
Synthesis of indoline-piperidinones via a novel Ugi, ring expansion, pseudo-Dieckmann condensation and rearrangement cascade reaction
An Ugi, ring expansion, pseudo-Dieckmann condensation and rearrangement cascade reaction was discovered for the synthesis of indoline-piperidinones in one pot. A series of targeted compounds was prepared by means of a mild reaction and a simple operation procedure, which could be applicable to a broad scope of Ugi starting materials. This cascade reaction generates opportunities for the tailored synthesis of a wide range of indoline-piperidinone scaffolds through tuneable Ugi inputs.
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