Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 99365-40-9, Name is 6-Bromoindolin-2-one. In a document, author is Hao, Yongjia, introducing its new discovery. Computed Properties of C8H6BrNO.
A highly efficient In(OTf)(3)-catalyzed [3+3] annulation of spirocyclopropyl oxindoles with 1,4-di-thiane-2,5-diol
Spirooxindoles play an important role in drug discovery and development. The development of efficient methods for the synthesis of spirooxindoles from easily available starting materials is of current interest. Herein, we report in detail the In(OTf)(3)-catalyzed [3 + 3] annulation of spirocyclopropyl oxindoles and 1,4-di-thiane-2,5-diol, which allows the facile preparation of spiro[indoline-3,4′-thiopyran]-2-ones bearing (tetrahydro)thiopyran skeleton. (C) 2019 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 99365-40-9 help many people in the next few years. Computed Properties of C8H6BrNO.