In an article, author is Cheng, Xiangsheng, once mentioned the application of 56341-37-8, HPLC of Formula: C8H6ClNO, Name is 6-Chlorooxindole, molecular formula is C8H6ClNO, molecular weight is 167.5923, MDL number is MFCD00209962, category is indolines-derivatives. Now introduce a scientific discovery about this category.
DABCO-Catalyzed alpha-Regio- and Diastereoselective (3+2) Cycloadditions of Nitrone Ylides from Isatins and Activated Alkenes
alpha-Regio- and diastereoselective (3+2) cycloadditions of nitrone ylides derived from isatins with activated alkenes have been demonstrated. This mild protocol allows rapid access to a wide range of 3 ‘,5 ‘-diaryl-1 ‘-hydroxy-2-oxospiro[indoline-3,2 ‘-pyrrolidine] derivatives by using DABCO as an efficient catalyst. This method could also be carried out through three-component reaction efficiently in good yields and excellent diastereoselectivity.
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