Adding a certain compound to certain chemical reactions, such as: 603-62-3, name is 3-Nitrophthalimide, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 603-62-3, HPLC of Formula: C8H4N2O4
Example 1 (best mode):; A solution of NaOH (2.0 mole) having a strength of 1 5% by weight was cooled to a temperature of 25C. Then 1 .0 mole of 3-nitro-phthalimide was added portionwise under stirring. While maintaining the temperature at 25-30C, 1 .2 mole solution of 12% strength sodium hypochlorite was added portionwise. During addition, the pH of the reaction mass was kept at pH 12.0 with aqueous sodium hydroxide with a concentration of of 15% by weight. After stirring for 2 hours, the reaction mass was cooled down to 5-10 C and acidified with 32% hydrochloric acid to a pH value of 1 .8. After stirring for another hour, the reaction mass was filtered with a suction filter. Then the cake was washed with cold water (8-10 C) and dried under vacuum to yield 6-nitro-anthranilic acid in an amount of 88% of theory.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Nitrophthalimide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; SYNGENTA PARTICIPATIONS AG; MURUDI, Vikrant; SHYADLIGERI, Ashok Shankarappa; MISHRA, Brijnandan Premnath; LUGINBUEHL, Markus Adolf; FUERST, Maren; WO2011/98386; (2011); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem