Related Products of 7477-63-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 7477-63-6, name is 7-Chloroisatin belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
5mmol of o-phenylenediamine in turn,5mmol 7-chloro-diketoindoline,6mmol of 2-iodopropane,1mmol p-toluenesulfonic acid,1mmol selective fluorine reagent,20ml of toluene was added to a round-bottomed flask, and the mixture was stirred at 70-90 C under reflux for 48 hours. After the reaction was completed, 30ml of saline was added to quench the reaction. The reaction mixture was extracted with 90ml of ethyl acetate three times. The filtrate was concentrated and separated by column chromatography to obtain analytically pure 7-chloro-6-isopropyl-6H-indole [2,3-b] quinoxaline. Red solid, 91% yield
The synthetic route of 7-Chloroisatin has been constantly updated, and we look forward to future research findings.
Reference:
Patent; South China Normal University; Guangzhou Huarui Optoelectric Materials Co., Ltd.; Song Xinlong; Zhou Guofu; Pan Junyou; (10 pag.)CN110283177; (2019); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem