2518-24-3, name is 4-Aminoisoindoline-1,3-dione, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 2518-24-3
(1) The solid phthalic anhydride and urea are added to the reactor and heated to 136 C for 320 seconds. The prepared o-aminobenzene dicarboximide is introduced into the first tubular reactor together with water and sodium hydroxide and forced cooled to -15 deg. C; The Hoffmann degradation reaction was carried out by adding methanol and sodium nitrite solution at 1: 0.5, the reaction time was 48 seconds, and then separating the o-aminobenzoic acid methyl ester;
The synthetic route of 2518-24-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Tian, Zixin; Tian, Zhenmin; Yang, Yuanxi; Wang, Jilong; Cui, Zhen; (6 pag.)CN105949091; (2016); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem