Adding a certain compound to certain chemical reactions, such as: 1504-06-9, name is 3-Methyloxindole, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1504-06-9, Recommanded Product: 1504-06-9
General procedure: In an open-air tube at room temperature (25 C), the corresponding 3-substitutedoxindole (0.15 mmol) was added to a solution of organocatalyst 5 (10 mol%) in toluene (1 mL). After 5 minutes, the mixture was introduced into a cooling bath at 0 C, andafter two minutes di-tert-butylazodicarboxilate (0.11 mmol, 1.1 eq.) was added in oneportion. The reaction was then allowed to react for 3 days. After this time, water (5 mL)and ethyl acetate (5 mL) were added, and the aqueous layer was then re-extracted twice (2 x 10 mL). The combined organic phases were dried (MgSO4) and evaporated underreduced pressure. Finally, the reaction crude was purified by column chromatographyon silica gel or TLC preparative using hexane/ethyl acetate mixtures as eluent. Spectroscopic data are listed within the article.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Methyloxindole, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Benavent, Lloren; Baeza, Alejandro; Freckleton, Megan; Molecules; vol. 23; 6; (2018);,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem