Related Products of 6872-06-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6872-06-6, name is 2-Methylindoline, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: The synthesis of 2-(6-(indolin-1 -yl)-6-oxohexyl)phthalimide 5.2.4 was performed following the report of Krasnov and co-workers ( see Krasnov et al., Mendeleev Commun. 25:412 (2015)): To a stirred solution of aniline (1 .0 equiv) and A/,A/-diethylaniline (1 .0 equiv) in 0.2 M dry CH2CI2was added a 0.2 M solution of acid chloride (1 .0 equiv) in dry CH2CI2dropwise over 10 min. After stirring at room temperature for 16 h, a 1 .0 N aq soln of HCI was added to the reaction mixture. After 30 min, the reactives were diluted with 20 ml. of EtOAc and washed with 2 c 20 ml. of water and 20 ml. of a 5% aq soln of NaHC03. The resulting organic phase was dried over Na2S04, filtered and the filtrate was concentrated in vacuo. The resulting residue was purified by MPLC to afford the product.
The chemical industry reduces the impact on the environment during synthesis 2-Methylindoline. I believe this compound will play a more active role in future production and life.
Reference:
Patent; THE BOARO OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE TRUSTEES OF INDIANA UNIVERSITY; DRIVER, Tom, G.; MACHADO, Roberto, F.; SU, Naijing; GUAN, Xinyu; MAZUMDAR, Wrickban; RATIA, Kira; HICKOK, Jason, Ralph; LOCKETT, Angelia, Denise; (159 pag.)WO2019/153007; (2019); A2;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem