Electric Literature of 603-62-3, These common heterocyclic compound, 603-62-3, name is 3-Nitrophthalimide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
In a 2500 mL round bottom flask containing 0.52 mol (100 g) of 3-nitrophthalimide, Add anhydrous ethanol 800mL, Under stirring, 385 mL of a methanolic solution of KOH at a concentration of 80 g ¡¤ L -1 (1 h addition, 0.55 mol KOH) was added dropwise and stirring continued for 3 h at room temperature, filter, The resulting white solid was rinsed with absolute ethanol, drying, The quality of 119g.
The synthetic route of 603-62-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Chinese Academy Of Agricultural Sciences Plant Protection Institute; Mei Xiangdong; Si Weijie; Zhang Tao; Ning Jun; (17 pag.)CN104447498; (2017); B;,
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