Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2058-74-4, name is 1-Methylisatin, A new synthetic method of this compound is introduced below., Recommanded Product: 2058-74-4
General procedure: A mixture of 20 mmol of isatine 1a-1f, malononitrile (2), 5,5-dimethylcyclohexane-1,3-dione (3) or 8-hydroxyquinoline (4) and 1 mL of aqueous trimethylamine in 80 mL of ethanol was stirred under reflux for 2 h, after which 40 mL of the solution was distilled off, and the remaining solution was left to stand in the cold. The crystals that formed were filtered off and recrystallized from ethanol.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Harutyunyan, A. A.; Pogosyan, M. V.; Pogosyan, S. A.; Russian Journal of Organic Chemistry; vol. 56; 2; (2020); p. 213 – 217; Zh. Org. Khim.; vol. 56; 2; (2020); p. 204 – 209,6;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem