Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 366453-21-6, name is 4-Hydroxy-2,3-dihydroisoindol-1-one, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 366453-21-6
k Synthesis of 2,3-dihydro-1H-isoindol-1-one (29): To a solution of 4-hydroxy 2,3-dihydro-1H-isoindol-1-one (27) (0.250 gm, 1.67 mmol) in DMF (5 ml) K2CO3 and was added, followed by addition of methyl bromoacetate, and the reaction mixture was stirred at room temperature for 2hr. Then the reaction mixture was then poured on ice and extracted with ethyl acetate (2*15 ml). After the standard workup, the residue was dissolved in methanol (3 ml), and treated with NaOH (5 ml, 1N) at 0 C. and then stirred for and additional hour. After the standard workup, the solid was recrystallized in methanol to give compound 29 (0.140 gm, 60%).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 366453-21-6.
Reference:
Patent; Jagtap, Prakash; Southan, Garry; Salzman, Andrew; Szabo, Csaba; Ram, Siya; US2002/95044; (2002); A1;,
Indoline – Wikipedia,
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