Formula: C8H7NO. Recently I am researching about PHOTOPROTOLYTIC OXAMETATHESIS; METATHESIS; CONFORMATION; NMR, Saw an article supported by the NIH/National Institute of General Medical SciencesUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R01-GM118644]; Alfred P. Sloan FoundationAlfred P. Sloan Foundation; David and Lucile Packard FoundationThe David & Lucile Packard Foundation; Camille and Henry Dreyfus Foundation; EU Horizon 2020 Marie Sklodowska-Curie Fellowship [792144]; NSFNational Science Foundation (NSF) [ACI-1548562]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Becker, MR; Reid, JP; Rykaczewski, KA; Schindler, CS. The CAS is 59-48-3. Through research, I have a further understanding and discovery of Indolin-2-one
Carbonyl-ene, Prins, and carbonyl-olefin metathesis reactions represent powerful strategies for carbon-carbon bond formation relying on Lewis acid catalysts. Although common Lewis acids are able to provide efficient activation, the reactions often proceed with low regio- or chemoselectivity, while high selectivity frequently requires the use of well-designed metal-ligand complexes. Here we demonstrate that simple Lewis acids including Me2AlCl, FeCl3, and SnCl4 can show remarkable selectivity in differentiating between distinct transformations of carbonyl and olefin functional groups, resulting in either carbonyl-ene or carbonyl-olefin metathesis products. Specifically, we report the development of predictive multivariate linear regression models that rely on kinetic and thermodynamic information obtained in DFT calculations to gain important insights into the complex potential energy surfaces (PES) of these competing reaction paths. The presented results further our understanding of Lewis acid reactivity and suggest that even simple Lewis acids have the potential to function as highly selective catalysts.
About Indolin-2-one, If you have any questions, you can contact Becker, MR; Reid, JP; Rykaczewski, KA; Schindler, CS or concate me.. Formula: C8H7NO
Reference:
Indoline – Wikipedia,
,Indoline | C8H9N – PubChem