Reference of 446292-08-6, Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes.
4.45 g (10.6 mmol) of the structural compound of formula (II) was suspended in 100 ml of ethanol, 40 ml of a methylamine aqueous solution (10.2 ml, 142 mmol) was added, reflux for 2 hours, concentrate to dryness under reduced pressure. Add 100 ml of ethanol, continue to concentrate under reduced pressure to dry. The residue was cooled to room temperature, adding 90 ml of methylene chloride, and the mixture was stirred to obtain a dichloromethane solution of the compound of the formula (R-1) go directly to the next step.
The potential utility of systematic synthetic strategy will be applicable to efficient generations of chemical libraries of compounds to find ‘hit’ molecules.Read on for other articles about 446292-08-6.
Reference:
Patent; Chongqing Ying Sikai Chemical Co., Ltd.; Chongqing Kerui Pharmaceutical (Group) Co., Ltd.; Huang Yuming; Wu Mingliang; Long Ping; Cheng Peng; Li Yang; Liu Junmin; Yue Xuerong; (10 pag.)CN106588905; (2017); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem