Introduction of a new synthetic route about 20870-78-4

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20870-78-4, name is 5-Bromoindolin-2-one, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 5-Bromoindolin-2-one

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20870-78-4, name is 5-Bromoindolin-2-one, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 5-Bromoindolin-2-one

Compound 43a (5 g, 23.7 mmol) was dissolved in 150 mL THF.Sodium carbonate (25 g, 23.5 mmol) and di-tert-butyl dicarbonate (12.8 g, 58.6 mmol) were added in that order.Reaction at 60 C for 12 h,After completion of the reaction, the mixture was filtered and purified by silica gel column chromatography to afford compound 43b (3.1 g).

According to the analysis of related databases, 20870-78-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Sichuan Kelun Botai Bio-pharmaceutical Co., Ltd.; Zhu Jiawang; Cai Jiaqiang; Li Guiying; You Zejin; Wu Yongyong; Han Runfeng; Ge Yong; Wang Lichun; Wang Jingyi; (49 pag.)CN109928979; (2019); A;,
Indoline – Wikipedia,
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