Synthetic Route of 1074-82-4, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1074-82-4 as follows.
Into a reaction vessel were put potassium phthalimide (5.00g, 27.0mmol), benzyltrimethylammonium chloride (0.50g, 2.70mmol) and tert -buyl alcohol (50ml) and then thereto was added (S)-epichlorohydrin (6.53g, 54.0mmol). The mixture was stirred at 20C for 24 hours and the solvent was removed. To the residue was added ethyl acetate (30ml), the mixture was washed with water (20ml), and then ethyl acetate was removed to give crude (S)-glycidylphthalimide (3.95g, yield: 72%, optical purity: 97%e.e.) as a white solid.
According to the analysis of related databases, 1074-82-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DAISO CO., LTD.; EP1403267; (2004); A1;,
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