The important role of 3335-98-6

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3335-98-6, name is 1-Phenyloxindole, This compound has unique chemical properties. The synthetic route is as follows., category: indolines-derivatives

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3335-98-6, name is 1-Phenyloxindole, This compound has unique chemical properties. The synthetic route is as follows., category: indolines-derivatives

N-phenyl-2-indolone (1a, 0.3 mmol), t-butyl nitrite (t-BuONO, 2a, 1.2 mmol) and water (2 mL) were added to 10 mL of Schlenk vials and the reactor 25 C under stirring conditions, The reaction was monitored by TLC or GC until the reaction with N-phenyl-2-indolone was complete and the reaction was stopped. The reaction was diluted with ethyl acetate, The organic phase was dried over anhydrous sodium sulfate, filtered and distilled under reduced pressure. The residue was separated by column chromatography (n-hexane / ethyl acetate). The organic phase was extracted with ethyl acetate and the organic phase was separated. Ester) to give the desired product N-phenyl-isato-3-oxime I-3, yield 89%

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 3335-98-6.

Reference:
Patent; Ningbo University; Wu Yi; Wei Wenting; Zhu Wenming; Huang Yiling; Wu Kewei; Cao Yiqi; Wang Yining; Zhu Liwei; (8 pag.)CN107162951; (2017); A;,
Indoline – Wikipedia,
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