In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 446292-07-5, name is (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 446292-07-5
Example – 6: Preparation of 2-5(S)-{2-Oxo-3-[4-(3-oxo-morpholin-4-yl) phenyl]- oxazolidin-5-ylmethyl}-isoindoIe-l,3-dione (III)60 gms of 2-{2-Hydroxy-3-[4-(3-oxo-mo holin-4-yl)phenylamino]-propyl}-isoindole- 1 ,3-dione and 180 ml of methylene chloride were charged into a clean and dry 4 neck R.B. flask. 29 gms of carbonyl diimidazole was added at about 30C and the resultant reaction mixture was stirred at about 30C for about 20 hours. After completion of the reaction, the reaction mixture was washed with water and the solvent was distilled completely to give 55gms of the title compound.
The synthetic route of 446292-07-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SYMED LABS LIMITED; MOHAN RAO, dodda; KRISHNA REDDY, pingili; ANNA REDDY, ambati; VENKAT REDDY, buthukuri; WO2012/32533; (2012); A2;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem