The origin of a common compound about 17630-75-0

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 17630-75-0, name is 5-Chloro-2-oxindole, A new synthetic method of this compound is introduced below., Product Details of 17630-75-0

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 17630-75-0, name is 5-Chloro-2-oxindole, A new synthetic method of this compound is introduced below., Product Details of 17630-75-0

A 5 mL of ethanol solution containing 5-chlorooxindole (167 mg, 1 mmol), 2- pyridine-carboxaldehyde (129 mg, 1.2 mmol) and 3 drops of piperidine was stirred at 80C for 6 hours. After cooling the solution to 5C, yellow precipitate was obtained (200 mg, 78%). MS: TITLE 257 [M+1] +.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; IRM LLC; THE SCRIPPS RESEARCH INSTITUTE; WO2004/37247; (2004); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem