The origin of a common compound about 1168150-46-6

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1168150-46-6 as follows. Computed Properties of C18H15NO4

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1168150-46-6 as follows. Computed Properties of C18H15NO4

(E)-methyl- 3-(methoxy(phenyl) methylene)-2-indolone-6- methyl formate (9-2) (200mg, 0.64mmol) and N- (4-aminophenyl) -N-methyl-2- (4- Trideutero methylpiperazin-1-substituted) acetamide (15-2) (171mg, 0.65mmol) in methanol (1.8mL) was refluxed for 8h , slowly cooled to 10 , stirring was continued at 10 1h, suction filtered, washed with cold methanol, and dried to give 310mg (89%) as a yellow solid, compound (Zeta)-3-((4-(Nu- methyl-2-(4- Trideutero methylpiperazin-1-substituted) acetamide)anilino(phenyl) methylene)-2-indolone-6- methyl formate

According to the analysis of related databases, 1168150-46-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Sichuan University; Chen, Yuanwei; Xie, Yongmei; Wei, Yuquan; (32 pag.)CN104003925; (2016); B;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem