Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 446292-08-6, name is (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C22H19N3O6
Add 4 kg of N,N-dimethylacetamide to a 10 L reaction flask.Add 1.0 kg of compound (II), add 1.4 kg of ethylenediamine, stir and heat.The reaction was stirred at 40 C for 4 h. The reaction solution was cooled to 30 ± 5 C,Add about 1.2kg of phosphoric acid, add the reaction, and cool the reaction solution to 10±5C for 1h~1.5h.Filtration, filter cake washed with N, N-dimethylacetamide, ethanol,The wet product was transferred to a blast oven, and the internal temperature of the oven was controlled to dry at 50-55 C for 16 ± 1 hour to obtain a white solid. Yield: 93%, product purity (HPLC): 99.5%.
According to the analysis of related databases, 446292-08-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Changzhou Pharmaceutical Factory Co., Ltd.; Guo Yijie; Jin Xiaofeng; Shao Zhichun; (13 pag.)CN110156768; (2019); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem